Postdoctoral fellow in cancer biology

The Cancer Research Center of Lyon (CRCL, directed by Dr. Mehlen, is a research unit accredited by Inserm, CNRS, Université Claude Bernard Lyon 1 and the Centre Léon Bérard. Comprising 25 teams and 13 technological platforms, its activities are dedicated to the study of cancer biology.

The goal of this postdoctoral fellowship is to characterize the molecular mode of action of a novel regulator of melanoma dissemination.

The successful candidate will work under the direction of the team leader, Julien Ablain, and will:

• Participate in project design; Develop and optimize experimental procedures; Perform experiments; Analyze and communicate data; Supervise students and technical staff

The techniques used may cover all areas of genetics, cellular and molecular biology and biochemistry. They will include genetic manipulations (RNA interference, CRISPR), transcriptomic and proteomic approaches, protein analysis (immunolabeling, Western blot, immunoprecipitation, purification), imaging (real-time and/or high-resolution confocal microscopy) and pharmacological studies in both zebrafish and human cells. The successful candidate will also implement all methods related to the use of zebrafish models.

• Work involving zebrafish will take place at the ENS Lyon animal facility on the Gerland site. An established collaboration provides access to clinical samples.

• Background in cancer biology appreciated; Training in animal experimentation preferred (but knowledge of zebrafish not required).

• Mastery of cell culture techniques; Basic methods in genetics, molecular and cell biology, and biochemistry.

• Motivation, independence, rigor, creativity; Ability to communicate and work in a team; Excellent level of English (written and spoken).

• Experience in cancer biology, genetics, molecular biology, cell biology or biochemistry.

• PhD or equivalent

Company

Founded in 1964, Inserm is a public scientific and technological institute which operates under the joint authority of the French Ministries of Health and Research. The institute is dedicated to biomedical research and human health, and is involved in the entire range of activities from the laboratory to the patient’s bedside. It also partners with the most prestigious research institutions in the world that are committed to scientific challenges and progress in these fields. Inserm brings together 15,000 researchers, engineers, technicians and administrative staff, all with one shared objective: improve health by advancing knowledge about living organisms and diseases, developing innovative treatment modalities and conducting research on public health.

Company info

Website

Telephone

+33144236277

Location

101 Rue de Tolbiac
Paris
Paris
75013
France